Lichen sclerosus is a chronic skin condition that most commonly affects the genital skin. The affected areas become thin, white, crinkled, irritated, and/or intensely itchy. Blisters and sores can also form. Left untreated, the condition can lead to scarring and can increase an individual’s risk for a type of skin cancer known as squamous cell carcinoma. Lichen sclerosus most commonly affects post menopausal women and pre-pubertal girls. Though the skin lesions can appear anywhere, it is most typically found on the vulva (area outside the vagina), perineum (area between the vulva and anus), and around the anus. Treatment options include various topical prescription medications.